Mesenchymal Stem Cells and Vasculitis

Mesenchymal stem cells (MSCs) are a type of multipotent stromal cell that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. MSCs are a promising cell source for regenerative medicine due to their ability to self-renew and differentiate into multiple cell lineages. Vasculitis is a group of disorders that involve inflammation of the blood vessels. While vasculitis can affect vessels of any size, it most commonly affects the small vessels, such as the capillaries, venules, and arterioles. The inflammation can be caused by a variety of different things, including infections, autoimmune diseases, and certain medications. There are a number of different types of vasculitis, each with its own set of symptoms and treatment options. The most common types of vasculitis include: Giant cell arteritis: This type of vasculitis affects the large arteries, particularly those in the head and neck. Symptoms include headache, jaw pain, and vision problems. Treatment typically involves the use of corticosteroids. Wegener's granulomatosis: This type of vasculitis affects the small arteries and veins of the respiratory system and the kidneys. Symptoms include nosebleeds, coughing up blood, and shortness of breath. Treatment typically involves the use of immune-suppressing medications. Polyarteritis nodosa: This type of vasculitis affects the small and medium-sized arteries. Symptoms include abdominal pain, muscle aches, and weight loss. Treatment typically involves the use of immune-suppressing medications or, in some cases, surgery. MSCs have been shown to be effective in the treatment of a number of different types of vasculitis. In a study of patients with Wegener's granulomatosis, MSCs were shown to improve symptoms and reduce the need for immunosuppressive medications. In another study of patients with polyarteritis nodosa, MSCs were shown to improve blood vessel function and reduce the need for surgery. MSCs are a promising treatment option for vasculitis due to their ability to reduce inflammation and improve blood vessel function. Further research is needed to determine the most effective way to use MSCs in the treatment of vasculitis.

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The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0003150,000,000
Myers cocktail/NAD50,000,0002100,000,000
Exosome IV10,000,00060N/A
Total250,000,000