Mesenchymal Stem Cells (MSCs) and Cataracts

Mesenchymal stem cells (MSCs) are a type of adult stem cell that can be found in many tissues throughout the body, including the bone marrow, adipose tissue, and even umbilical cord blood. MSCs have the ability to differentiate into a variety of cell types, including adipocytes, osteocytes, chondrocytes, and myocytes, making them versatile tools for regenerative medicine. One potential use of MSCs is in the treatment of cataracts. Cataracts are a leading cause of blindness worldwide, and current treatment options are limited to surgery. MSCs have the ability to differentiate into lens cells, and theoretically could be used to replace the damaged lens cells in patients with cataracts. MSCs have been shown to be safe and effective in animal models of cataracts, and clinical trials are currently underway to test the safety and efficacy of MSCs in humans. If proven safe and effective, MSCs could revolutionize the treatment of cataracts and other blinding eye diseases.

 "A Review on Mesenchymal Stem Cells for Treatment of Retinal ...." 6 Jan. 2021, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787584/. Accessed 21 Oct. 2022.

 "Empowering Mesenchymal Stem Cells for Ocular Degenerative ...." 10 Apr. 2019, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480671/. Accessed 21 Oct. 2022.

 "Interaction Between Mesenchymal Stem Cells and Retinal ...." 17 Dec. 2020, https://www.frontiersin.org/articles/10.3389/fnins.2020.617377/full. Accessed 21 Oct. 2022.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0003150,000,000
Intrathecal20,000,000120,000,000
Exosome Eye Drops10,000,0001N/A
Total170,000,000