Ovarian Cysts and Stem Cells

Ovarian cysts are fluid-filled sacs or pockets in the ovary or on its surface. Cysts can range in size from a pea to a grapefruit. A cyst can form in one ovary or both ovaries. Mesenchymal stem cells (MSCs) are a type of adult stem cell that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells), and adipocytes (fat cells). MSCs can be isolated from a variety of tissues, including: bone marrow, adipose tissue, and umbilical cord tissue. Cysts can cause a number of symptoms, including: • Pelvic pain • Abnormal bleeding • Fullness or bloating in the abdomen • Nausea • Vomiting • Pain during sex • Difficulty urinating • Infertility In some cases, a cyst can rupture, causing: • Severe pain • Nausea • Vomiting • Lightheadedness • Fever If a cyst ruptures, it can also lead to inflammation of the ovary (oophoritis) or the formation of scar tissue (adhesions). Cysts can be benign (non-cancerous) or malignant (cancerous). Benign cysts are much more common than malignant cysts. Most cysts do not require treatment and will resolve on their own. However, if a cyst is causing symptoms or is at risk of rupturing, it may need to be removed. 

The use of MSCs in the treatment of ovarian cysts is still in the early stages of research. However, MSCs hold promise as a potential treatment for ovarian cysts. MSCs can be injected into the ovary or directly into the cyst. Injecting MSCs into the ovary may help to prevent the formation of new cysts. Injecting MSCs directly into the cyst may help to shrink the cyst and reduce symptoms. 

The use of MSCs in the treatment of ovarian cysts is still in the early stages of research. However, MSCs hold promise as a potential treatment for this condition.

 "Stem Cell Contribution to Ovarian Development, Function ... - NCBI." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553384/. Accessed 24 Oct. 2022.

 "CD24 and Nanog identify stem cells signature of ovarian epithelium ...." https://pubmed.ncbi.nlm.nih.gov/24103524/. Accessed 24 Oct. 2022.

 "Ovarian stem cells: absence of evidence is not evidence of absence." 17 Sep. 2013, https://ovarianresearch.biomedcentral.com/articles/10.1186/1757-2215-6-65. Accessed 24 Oct. 2022.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0004400,000,000
Myers cocktail/NAD1N/A
Periovarian50,000,000150,000,000
Total450,000,000