Stem Cells and Inflammatory Bowel Disease

Mesenchymal stem cells (MSCs) are a type of stromal cell that can be found in various tissues throughout the body, including the bone marrow, adipose tissue, and even the umbilical cord. These cells have the ability to self-renew and differentiate into a variety of cell types, making them a promising tool for regenerative medicine. MSCs have been shown to be effective in treating a variety of diseases, including inflammatory bowel disease (IBD). IBD is a chronic, inflammatory condition of the gastrointestinal tract that affects approximately 1.6 million people in the United States. The two most common types of IBD are Crohn's disease and ulcerative colitis. There is currently no cure for IBD, and treatment options are often limited to medications that can help to manage the symptoms. These medications can have serious side effects, and they are not always effective. This is why there is a need for new, innovative treatments for IBD. MSCs have the ability to modulate the immune response, making them a potential treatment for IBD. In a study on mice with Crohn's disease, MSCs were able to reduce the inflammation in the intestine and improve the symptoms of the disease. MSCs have also been shown to be effective in treating ulcerative colitis. In a clinical trial, patients with ulcerative colitis who were treated with MSCs showed a significant improvement in their symptoms. The use of MSCs in the treatment of IBD is still in its early stages, but the results so far are promising. MSCs offer a new, potential treatment option for IBD that is safe and effective.

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 "Stem Cell-Based Therapies for Inflammatory Bowel Disease - PubMed." 31 Jul. 2022, https://pubmed.ncbi.nlm.nih.gov/35955628/. Accessed 21 Oct. 2022.

 "Researchers use stem cell technology to replicate diseased human ...." 17 Dec. 2021, https://www.crohnscolitisfoundation.org/stem-cell-therapy-fibrosis-IBD. Accessed 21 Oct. 2022.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0004200,000,000
Myers cocktail/NAD50,000,0001N/A
Pericolonic50,000,000150,000,000
Total250,000,000