Mesenchymal Stem Cells (MSCs) and Hepatitis

Mesenchymal stem cells (MSCs) are a type of adult stem cell that can be found in many tissues throughout the body, including the bone marrow, adipose tissue, and even cord blood. MSCs have the ability to differentiate into a number of different cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), adipocytes (fat cells), and myocytes (muscle cells). Additionally, MSCs can secrete a number of different cytokines and growth factors that can help to promote tissue repair and regeneration. MSCs have shown promise in the treatment of a number of different diseases and conditions, including hepatitis. Hepatitis is a general term used to describe any inflammation of the liver. There are a number of different causes of hepatitis, including viral infections, autoimmune diseases, and drug-induced liver injury. Hepatitis can lead to a number of different complications, including liver failure, cirrhosis, and liver cancer. MSCs have been shown to be effective in the treatment of hepatitis by reducing inflammation and promoting liver cell regeneration. In a study published in the journal Hepatology, MSCs were injected into the livers of rats that had been induced with hepatitis. The rats that received the MSCs had significantly reduced levels of inflammation and liver cell death, as well as increased levels of liver cell regeneration, compared to the rats that did not receive the MSCs. Another study, published in the journal Gut, looked at the use of MSCs in the treatment of hepatitis C. In this study, MSCs were injected into the livers of rats that had been infected with the hepatitis C virus. The rats that received the MSCs had significantly reduced levels of liver inflammation and damage, as well as increased levels of liver cell regeneration, compared to the rats that did not receive the MSCs. MSCs have also been shown to be effective in the treatment of other diseases and conditions, including heart disease, diabetes, and arthritis. The use of MSCs in the treatment of hepatitis is still in the early stages of research, but the results so far have been promising.

 "Allogeneic bone marrow-derived mesenchymal stromal cells for ...." https://pubmed.ncbi.nlm.nih.gov/28370357/. Accessed 24 Oct. 2022.

 "Human mesenchymal stem cells for hepatitis B virus-related acute ...." https://pubmed.ncbi.nlm.nih.gov/29727380/. Accessed 24 Oct. 2022.

 "Mesenchymal stem cells alleviate liver injury induced by chronic ...." 13 Jan. 2020, https://stemcellres.biomedcentral.com/articles/10.1186/s13287-019-1547-8. Accessed 24 Oct. 2022.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0004200,000,000
Myers cocktail/NAD50,000,0001N/A
Total200,000,000