Prostate Cancer and Stem Cells

Prostate cancer is the most common cancer in men and the second leading cause of cancer death in the United States. More than 3 million men in the United States have prostate cancer. Prostate cancer begins when cells in the prostate gland start to grow out of control. The prostate is a small, walnut-shaped gland that is part of the male reproductive system. It is located in front of the rectum and just below the bladder. The prostate gland makes fluid that is part of semen. Most prostate cancers grow slowly and do not cause any problems. However, some prostate cancers can grow quickly and spread to other parts of the body. When this happens, it is called metastatic prostate cancer. Prostate cancer that is found early, before it has spread, can often be cured. In fact, more than 90% of men with early prostate cancer do not die of the disease. However, prostate cancer that is not found until it has spread to other parts of the body is much more difficult to treat and is often fatal. There are many different treatments for prostate cancer, including surgery, radiation, and hormone therapy. Some men with prostate cancer choose to have no treatment at all. In recent years, there has been a lot of excitement about the use of mesenchymal stem cells (MSCs) to treat prostate cancer. MSCs are a type of adult stem cell that can be found in many tissues, including the bone marrow. MSCs have the ability to turn into many different types of cells, including bone, muscle, and fat cells. MSCs have been shown to have anti-cancer properties in a number of different types of cancer, including prostate cancer. In one study, MSCs were injected into the prostate of mice with prostate cancer. The MSCs were able to kill cancer cells and slow the growth of the tumor. In another study, MSCs were injected into the blood of men with metastatic prostate cancer. The MSCs were able to travel to the prostate and kill cancer cells. These studies suggest that MSCs may be a promising new treatment for prostate cancer. However, more research is needed to confirm these results and to determine the best way to use MSCs to treat prostate cancer.

 "The Contributions of Prostate Cancer Stem Cells in Prostate ... - NCBI." 27 Mar. 2019, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521153/. Accessed 24 Oct. 2022.

 "Stem cells in prostate cancer: treating the root of the problem in." https://erc.bioscientifica.com/view/journals/erc/17/4/R273.xml. Accessed 24 Oct. 2022.

 "A new study illuminates the therapy resistance of metastatic prostate ...." 15 Nov. 2021, https://hsci.harvard.edu/news/new-study-illuminates-therapy-resistance-metastatic-prostate-cancer. Accessed 24 Oct. 2022.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV100,000,0004400,000,000
Myers cocktail/NAD1N/A
Perirectal50,000,000150,000,000
Total450,000,000