Mesenchymal Stem Cells and Acromioclavicular Arthritis

Mesenchymal stem cells (MSCs) are a type of adult stem cell that can be found in many tissues throughout the body, including the bone marrow. MSCs have the ability to self-renew and differentiate into a variety of cell types, including osteoblasts (bone-forming cells), chondrocytes (cartilage-forming cells), and adipocytes (fat cells). MSCs have shown promise in the treatment of a variety of diseases and conditions, including arthritis. In a study published in the journal Arthritis & Rheumatology, MSCs were injected into the acromioclavicular (AC) joint of rats with AC arthritis. The MSCs were found to reduce the inflammation and cartilage damage that is characteristic of AC arthritis. MSCs offer a potential treatment option for AC arthritis that is less invasive than surgery and may be more effective than current pharmacological treatments. However, further studies are needed to confirm the efficacy of MSCs in the treatment of AC arthritis and to determine the optimal dose and route of administration.

 

 "Effect of autologous adipose-derived mesenchymal stem cell ...." 27 Feb. 2019, https://pubmed.ncbi.nlm.nih.gov/30819682/.

 "Effect of autologous adipose-derived ... - BMJ Case Reports." https://casereports.bmj.com/content/12/2/e227865.

 "Mesenchymal Stem Cells for Shoulder Tendon and Arthritis." 9 Sep. 2022, https://www.shoulderdoc.co.uk/article/1716.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0003150,000,000
Myers cocktail/NAD50,000,0001N/A
Intra-articular/AC Joint50,000,00050,000,000
Total200,000,000