Stem Cells and Back Pain

Stem cells are unique cells with the ability to self-renew and differentiate into various specialized cell types. This makes them promising candidates for use in regenerative medicine and tissue engineering. In particular, stem cells can be used to repair and replace damaged tissue, which has led to their investigation as a potential treatment for a variety of degenerative diseases and injuries, including back pain. The most common type of stem cell used in research is the embryonic stem cell (ESC). These cells are derived from embryos that are three to five days old and have the ability to differentiate into any cell type in the body. This makes them ideal for use in regenerative medicine, as they have the potential to repair or replace any damaged tissue in the body. However, the use of ESCs is controversial, as their production requires the destruction of human embryos. An alternative to ESCs are adult stem cells (ASCs). These cells are found in adult tissues and have the ability to self-renew and differentiate into a limited number of cell types. ASCs are a promising source of cells for regenerative medicine, as they can be obtained from patients without the ethical concerns associated with ESCs. Additionally, ASCs have been shown to be effective in the treatment of a variety of diseases and injuries, including back pain. There are two main types of ASCs: hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). HSCs are found in the bone marrow and have the ability to self-renew and differentiate into all types of blood cells. MSCs are found in a variety of tissues, including the bone marrow, adipose tissue, and umbilical cord. They have the ability to self-renew and differentiate into a variety of cell types, including bone, cartilage, and fat cells. Both HSCs and MSCs have been shown to be effective in the treatment of back pain. HSCs have been used to treat degenerative disc disease, while MSCs have been used to treat facet joint arthritis. In both cases, the stem cells are injected into the affected area, where they differentiate into the appropriate cell type and replace the damaged tissue. This results in a reduction in pain and an improvement in function. The use of stem cells in the treatment of back pain is a promising new approach that has the potential to provide relief for a wide range of patients. However, additional research is needed to determine the long-term safety and efficacy of this treatment.

 "Intradiscal Stem Cell Injections for Low Back Pain." 25 Mar. 2019, https://twincitiespainmanagement.com/blog/intradiscal-stem-cell-injections-low-back-pain. Accessed 24 Oct. 2022.

 "How Can Stem Cell Treatment Help With Back Pain? - SpineINA." http://spineina.com/blog/stem-cell-therapy-for-back-pain/. Accessed 24 Oct. 2022.

 "Can Stem Cell Treatment Relieve My Back Pain?." https://www.integratedspineandpaincare.com/blog/can-stem-cell-treatment-relieve-my-back-pain. Accessed 24 Oct. 2022.

The information below is the recommended stem cell therapy protocol for this condition 

Route of AdministrationDoseTime (Days)Total Cells
IV50,000,0003150,000,000
Myers cocktail/NAD50,000,0002N/A
Exosome IV10,000,00060N/A
Intrathecal (site of injury)50,000,000150,000,000
Spinal Level/Intra discal50,000,000150,000,000
Total250,000,000